Platelet-rich plasma from your own blood, used for early-to-moderate knee arthritis — offered only when your X-ray and examination suggest it can help.
Book Clinic AppointmentPRP (platelet-rich plasma) is a concentrate of platelets prepared from your own blood and injected into the knee. Platelets release growth factors that may reduce inflammation and pain. It is a day-care procedure — about an hour, no admission, and you walk home the same day. At ONE Healthcare Clinic, Tirumalagiri, Secunderabad, PRP is offered for early-to-moderate (Grade 2–3) knee arthritis and some tendon problems, after an examination and X-ray by Dr. Sumit Dubewar.
Usually 1–3 sessions are given, about 4–6 weeks apart, depending on severity. Some patients receive PRP combined with hyaluronic acid. For selected Grade 2–3 knees, bone-marrow (BMAC) or fat-derived (mFAT) concentrate prepared from your own tissue may be discussed.
The evidence is encouraging but not uniform. Several systematic reviews and meta-analyses have found that PRP gives better pain and function scores at 6–12 months than hyaluronic acid or steroid injections in early-to-moderate knee osteoarthritis. However, at least one well-conducted randomised trial (published in JAMA, 2021) found no clear benefit over a saline injection at 12 months. Results also depend on how the PRP is prepared and on the stage of arthritis.
What this means for you: PRP is a reasonable option to reduce pain and improve function in Grade 2–3 knees when exercise alone isn’t enough. It does not regrow cartilage or reverse the X-ray grade, and not everyone responds. Dr. Sumit will tell you if your knee is unlikely to benefit.
PRP आपके अपने खून से बनाया गया इंजेक्शन है, जो Grade 2–3 घुटने के गठिया में दर्द कम करने और चलने-फिरने में मदद कर सकता है। यह कार्टिलेज वापस नहीं उगाता और Grade 4 में सलाह नहीं दी जाती। Dr. Sumit Dubewar, ONE Healthcare Clinic, तिरुमलगिरी, सिकंदराबाद।
PRP మీ స్వంత రక్తం నుండి తయారుచేసే ఇంజెక్షన్. Grade 2–3 మోకాలి ఆర్థరైటిస్లో నొప్పి తగ్గించి, నడకను మెరుగుపరచడంలో సహాయపడవచ్చు. ఇది కార్టిలేజ్ను తిరిగి పెంచదు; Grade 4లో సిఫారసు చేయబడదు. Dr. Sumit Dubewar, ONE Healthcare Clinic, తిరుమలగిరి, సికింద్రాబాద్.
The injection itself is brief. Mild to moderate soreness or stiffness for 1–3 days afterwards is common and is managed with ice packs and paracetamol.
Usually 1–3 sessions, spaced about 4–6 weeks apart, depending on the severity of arthritis and your response.
In studies of early-to-moderate knee arthritis, benefit has commonly been reported for 6–12 months, sometimes longer. Response varies between individuals and some people do not respond.
In Grade 2–3 arthritis, PRP combined with exercise may reduce pain enough to delay surgery. It does not regrow cartilage, and it is not recommended in Grade 4 (bone-on-bone) arthritis, where knee replacement is usually the better option.
PRP is made from your own blood, so allergy or rejection is unlikely. Temporary pain and swelling are common; infection is rare but possible, which is why the injection is done under strict sterile conditions.
Dr. Sumit Dubewar, orthopaedic surgeon with DABRM (USA) certification in regenerative medicine, offers PRP at ONE Healthcare Clinic (OrthoRegen), Tirumalagiri, Secunderabad. Appointments: +91 93704 98182 (phone or WhatsApp).
ONE Healthcare Clinic does not offer cashless insurance; PRP is paid directly. The cost and number of sessions are explained at consultation before you decide.
MBBS, DNB (Orthopaedics), FIJR (joint replacement fellowship), FIASM (arthroscopy & sports medicine fellowship), MNAMS, DABRM (USA) — 10+ years in orthopaedics.
Dr. Sumit provides non-surgical, regenerative and surgical knee care, including knee replacement; the options suitable for your knee are discussed at consultation. Consultations in English, Hindi, Telugu and Marathi.
This page is for patient education and does not replace an in-person consultation. Results of any treatment vary from person to person. Medically reviewed by Dr. Sumit Dubewar · Last reviewed 23 October 2026. Disclaimer
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