Regenerative treatments for early-to-moderate joint arthritis, using biological products prepared from your own body.
"The aim is to support the joint's own healing response — results vary from patient to patient."
Anti-inflammatory tablets and cortisone injections mask pain — they do not repair damaged cartilage. Some studies suggest repeated cortisone injections may be linked to faster cartilage loss.
Joint replacement is a major operation with real risks — anaesthesia, infection, blood clots, implant loosening. It should be the last option — not the default answer for Grade 1-3 arthritis.
Cartilage has poor blood supply — that's why it heals slowly. Regenerative therapy delivers concentrated healing signals directly to the damaged area, which may support the joint's healing response. Research on how much repair actually occurs is ongoing.
Think of your joint as a building that has developed cracks. Your blood naturally sends a few repair workers — but not enough to fix major damage.
Regenerative therapy is like sending a larger, concentrated team of workers directly to the damaged area. How much they can repair differs from patient to patient.
Think of your blood as a river carrying construction workers called platelets. Each platelet carries tiny packets of repair instructions called growth factors — like building materials. Normally, when your joint is damaged, only a few workers reach the site. PRP concentrates these workers 5-7 times and injects them exactly where the damage is — like calling an entire construction crew to one specific pothole instead of the whole city.
Blood Draw — 30ml from your arm (same as a routine blood test)
Centrifuge — Blood spun at high speed. Red cells sink to bottom. Platelets concentrate at top
Collect PRP Layer — The platelet-rich layer is carefully collected. 5-7x more concentrated than normal blood
Inject — Under ultrasound guidance, directly into the damaged joint or tendon
Done — Usually a day-care procedure.
Range reported in published studies of PRP for Grade 1–3 knee OA (pain improvement at 6 months). Individual results vary.
Months — typical duration of effect reported in studies; varies by patient
Injections in a series for knee OA, spaced 4-6 weeks apart
Bone marrow, inside your pelvic bone, contains growth factors and other biological components. PRP uses repair signals from your blood. BMAC uses your own bone marrow — a small amount is taken, concentrated, and injected into the affected joint to support its healing response. How much repair occurs varies from patient to patient.
Local anaesthesia to the back of the pelvis. Patient awake, no general anaesthesia
Bone marrow aspiration — 30-60ml drawn from the iliac crest (pelvis). Minor discomfort, not severe pain
Centrifuge processing — The marrow is concentrated. Growth factors retained
Image-guided injection — Under fluoroscopy or ultrasound, directly into the joint
Day-care procedure — Many patients typically walk within hours and go home the same day
Contains platelets + growth factors. Reduces inflammation, activates healing signals. Does not generate new cells.
Contains bone marrow cells + growth factors. Studied for reducing inflammation and supporting cartilage repair. Evidence is still developing.
Avascular Necrosis (AVN) of the hip is a condition where the blood supply to the femoral head is cut off — the bone begins to die. When caught early (Stage 1-2), combining BMAC with Core Decompression (drilling small tunnels to restore blood supply) can prevent femoral head collapse and potentially avoid hip replacement completely. This is one of the most impactful uses of regenerative medicine in orthopaedics.
Years — duration of effect reported in published studies; varies by patient
Procedure in most protocols. Follow-up visits are still needed
Typical indication — moderate arthritis, after clinical evaluation
Most people think of fat as just stored energy. But fat tissue also contains anti-inflammatory molecules and supportive tissue. MFAT is like taking a small piece of your fat (from the abdomen — only 60-100ml, tiny amount), micro-shredding it into tiny fragments, and injecting it into the joint. The fat matrix acts as a biological scaffold — it may help modulate inflammation in the joint. Results vary between patients.
Local anaesthesia to the abdomen. No general anaesthesia required
Micro-lipoaspiration — 60-100ml fat removed from abdomen (comparable to a lipstick cap in volume)
Lipogems processing — Fat passed through special filtering device. No lab, no centrifuge needed. Produces micro-fragmented fat
Injection — Under ultrasound guidance into the joint. Fat fragments settle as a biological scaffold
Under 90 minutes total — Same day. No hospital stay.
Micro-fragmented fat acts as a cushioning biological scaffold in the joint.
IL-10, TGF-β — inflammation-modulating molecules.
The supporting framework of the fat tissue.
Grade 1-2 OA, tendon problems, early disease, first treatment attempt
Grade 2-3, cartilage defects, AVN, young active patient
Grade 2-3 OA, after PRP, multiple joints
Typical indication — early-to-moderate arthritis
Years — duration of benefit reported in studies; varies by patient
Minutes — total procedure time from start to finish
Surgery is considered when other options are not suitable or have not helped.
Weight management, targeted exercises, activity modification. First step for every grade.
All Grades · First stepGrade 1-3. 3 injections over 12 weeks. Studies show better 12-month results than cortisone in many patients.
Grade 1-3 · Day procedure · 3 sessionsGrade 2-3 with cartilage defects. Single procedure. Uses your own bone marrow or fat.
Grade 2-3 · Single procedure · 3-5 yearsGrade 4 — bone on bone. Robotic-assisted joint replacement when indicated.
Grade 4 · When indicatedDr. Sumit holds the DABRM (Diplomate, American Board of Regenerative Medicine) . Treatment protocols follow published evidence, and each recommendation is discussed with what the evidence shows, what to expect, and the alternatives.
Suitability is decided after examination and X-ray/MRI. Consultations are at ONE Healthcare Clinic, Tirumalagiri, Secunderabad · Phone: +91 9370498182.